The concept of modern public health was introduced to China in the mid-19th century with the spread of Western medicine. In the early 1920s, dreaming to develop public health undertakings, John B. Grant came to China where he made public health education his top priority. In his early years in China, with great dedication, John Grant began to carry out various activities. He tried to influence government officials, spread public health knowledge among educational administrators, and created a public health program in the Peking Union Medical College (PUMC). Not only did these efforts effectively promote the circulation of public health knowledge in China, but they also laid a solid foundation and trained qualified personnel for the field's sustainable development.