Alzheimer's disease (Alzheimer's, AD) is the sixth leading cause of death in the United States (U.S.), claiming the lives of more than 500,000 individuals each year. Today, approximately 5.3 million Americans are living with this disease. AD burdens the U.S. with a project economic cost of $226 billion in 2015, and is on pace to cost $1.1 trillion in 2050. Although AD is widely recognized as an epidemic by individual nations as well as by the World Health Organization, progress in AD clinical research and integrated care has been modest at best. Key challenges to combating this disease include:
- Poor understanding of disease onset and progression
- Gaps in funding to support high-risk research efforts
- Insufficient research tools and companion resources
- Lack of disease-modifying treatments
- What are key facts about the disease?
- Why is it important to invest in AD research?
- What is the current state of care?
- What is the current state of research?
- What are major barriers to progress?
- How can philanthropy advance a cure for AD?
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