This document has been published as a guide to develop coalitions that draw on the strengths and assets of communities of color. Although focused on the elimination of health disparities and the achievement of expanded access, the guidance presented is transferable to other issues as well. Coalition-building strategies, steps, and tools in the guide emerged from consultations with more than 100 representatives of regional and state Office of Minority Health contacts and members of Out of Many, One, a national multicultural advocacy organization. If this collective guidance is followed, the result can be partnerships that are strong, effective change agents over time. Such coalitions, constructed with care and commitment, will illustrate the Korean proverb: "One chopstick breaks easily. Many chopsticks cannot be broken."