Published jointly with The National Campaign to Prevent Teen Pregnancy, this report provides guidance about the replication of effective pregnancy prevention programs. It urges stakeholders to ask a variety of key questions when considering replication: Is the program effective? (What kind of evaluation has been done and what did it show?) What are the essential elements that make the program effective? Is the program ready to be replicated (with clear documentation)? And what is the replication plan? The report gleans lessons from the replication experiences of three programs: The Teen Outreach Program, The CAS-Carrera Program, and Plain Talk, whose national replication is being managed by P/PV.