In the Bering Sea, science-based management of major fisheries is designed to control fishing at levels that maintain stable populations of valuable fish. But a single-species approach to managing fisheries does not always consider the interconnections among marine organisms. Many scientists argue that although good single-species management is necessary, fishery managers also need to look at the bigger picture. Ecosystem-based fisheries management is a way to sustain the health of our oceans by accounting for the interconnections among marine life, an ever-changing environment, and human activities including commercial, recreational, and subsistence fishing. Tools and approaches to aid in ecosystem-based fisheries management are available to reduce bycatch; conserve important habitat; protect marine food webs; monitor ecosystem health; and evaluate the ecological, social, and economic trade-offs of different management actions. In the Bering Sea, many of these tools are being applied. Yet more will be needed to steward this ecosystem in the years ahead. As our knowledge of the Bering Sea ecosystem grows, as demand for seafood increases, and as impacts of climate change are felt, fishery managers must put a long-term plan in place to address the challenges the future will bring.