Too many children experience abuse and neglect with negative lifelong consequences. Too few children get the services and supports they need to heal. Yet, proven and promising practices can reduce maltreatment and ameliorate harm. Taking these practices to scale will require federal investment and leadership in five strategic areas. We must: (1) increase prevention and early intervention services that help keep children and families out of crisis; (2) increase specialized treatment services for those children and families that do experience crisis; (3) increase services to support families after a crisis has stabilized (including birth families, as well as kinship and adoptive families created when parents are unable to care for their children); (4) enhance the quality of the workforce providing services to children and families; and (5) improve accountability both for dollars spent and outcomes achieved. Together these efforts will improve the lives of millions of children across the nation.