The Plain Talk model is designed to improve adults' communication with teens about responsible sexual behavior. This publication is a "Training of Trainers" manual for "Walkers and Talkers" and "Home Health Parties," and is a companion piece to the Plain Talk Implementation Guide. This manual provides trainers with the information and materials they need to conduct training sessions for neighborhood residents. It is organized around core training topics, such as adolescent development, family communication, and reproductive health. Every topic includes an overview of the learning objectives and training tools such as lesson plans, sample lectures, and role plays. These training materials were designed by the original Plain Talk sites and found to be effective in diverse neighborhoods, particularly African American and Latino communities.